Neonatal Coinfection Model of Coagulase-Negative Staphylococcus ( Staphylococcus epidermidis ) and Candida albicans : Fluconazole Prophylaxis Enhances Survival and Growth
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چکیده
منابع مشابه
Investigation of linezolid resistance in Staphylococcus epidermidis: first reported linezolid resistant coagulase negative staphylococcus in Turkey.
Linezolid is a member of oxazolidinons and it inhibits protein synthesis at the initiation step. In this step, formation of 70S complex occurs by association of 50S ribosomal subunit, and 30S initiation complex, which is made of 30S ribosomal subunit, mRNA, and methionine carrying tRNA. Linezolid prevents this formation by binding the 50S subunit (1–3). Although it is a new agent, resistance ha...
متن کاملEffect of the imidazole derivative lombazole on the ultrastructure of Staphylococcus epidermidis and Candida albicans.
Lombazole, an antimicrobial agent of the imidazole class, induced profound ultrastructural changes in Staphylococcus epidermidis and Candida albicans, as observed by freeze fracture electron microscopy. In S. epidermidis cells, the primary effect on ultrastructure was characterized by a distinct change in the morphology of the plasma membrane. Secondary effects of lombazole were cell wall thick...
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The arylomycins are a class of natural-product antibiotics that act via the inhibition of type I signal peptidase (SPase), and we have found in diverse bacteria that their activity is limited by the presence of a resistance-conferring Pro residue in SPase that reduces inhibitor binding. We have also demonstrated that Staphylococcus epidermidis, which lacks this Pro residue, is extremely suscept...
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Herein, we describe the isolation of Staphylococcus pasteuri, Staphylococcus pettenkoferi and Staphylococcus gallinarum and summarize the clinical characteristics of five patients. Cases were identified over a 2-year surveillance period that identified the respective strains using microbiologic and molecular methods. These data suggest that rare coagulase-negative staphylococcal infections may ...
متن کاملCoagulase-negative strains of Staphylococcus pyogenes.
The isolation of two coagulase-negative strains of Staphylococcus pyogenes is reported, and their biochemical characteristics are given. The reliability of coagulase tests alone in the identification of Staph. pyogenes is discussed, and the deoxyribonuclease test is recommended as a useful confirmatory test.
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2007
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01298-06